Yes, but all it does really is eliminate the midrange. Some work better than others, but it all depends on what's in the midrange
If the voice is higher than a certain pre-set hertz, it won't filter out. For example, 311 has a singer and a rapper. The rapper, SA, has a really high pitched voice. The singer is eliminated, but the rapper remains.
Google some free "vocal removal" software programs.
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